Hemophagocytic Lymphohistiocytosis Occurring after Induction Chemotherapy in Acute Myelocytic Leukemia
نویسندگان
چکیده
منابع مشابه
Acute myelocytic leukemia in a patient with hemophagocytic lymphohistiocytosis: A case report
Hemophagocytic lymphohistiocytosis (HLH), also known as hemophagocytic syndrome, is an aggressive hyperinflammatory condition characterized by prolonged fever, cytopenias and hepatosplenomegaly, as well as hemophagocytosis by activated, morphologically benign macrophages. HLH may be characterized into two forms, familial and secondary HLH. Familial HLH usually manifests in children with genetic...
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Acute myelocytic leukemia (AML) in both children and adults is a more complex and resistant disease than acute lymphocytic leukemia. Progress has been slower and therapy more complicated, but with intensive myelosuppressive induction and further postremission therapy one-third of such patients may now achieve longterm survival and probably be cured.’-5 In the Nordic countries (Denmark, Finland,...
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A 46-year-old man was referred for acute myelocytic leukemia (AML) and pneumonia. On admission, physical examination findings included high fever and hepatosplenomegaly. The peripheral blood count results were as follows: hemoglobin level, 7.9 g/dL; platelet count, 7 3 10/L; and white blood cell count, 17.8 3 10/L (blasts, 37%). Bone marrow aspiration showed a hypercellular marrow with 60% myel...
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Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome of excessive immune activation, which is characterized by fever, hepatosplenomegaly, cytopenias, hyperferritinemia, hypertriglyceridemia, and/or hypofibrinogenemia, and evidence of hemophagocytosis. Secondary HLH is often seen in adults and categorized based on autoimmune, infections-related, and malignancy-associated etiol...
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Marrow specimens obtained from 23 patients with acute myelocytic leukemia were exposed to cytosine arabinoside and/or daunorubicin in vitro, and the effects of these agents on colony formation in vitro was determined. Thymidine suicide indices were determined as well, which permitted a distinction to be made between kinetic and metabolic resistance to cytosine arabinoside. The sensitivity of th...
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ژورنال
عنوان ژورنال: The Korean Journal of Medicine
سال: 2016
ISSN: 1738-9364,2289-0769
DOI: 10.3904/kjm.2016.91.1.79